Generic medicine
Bacopa extract [Natural memory enhancer]
This syrup is indicated in deficit/Cognitive deficit, Age Associated Memory Impairment (AAMI), Attention Deficit Disorder (ADD), Dementia, Convulsion and Epilepsy in children, Alzheimer’s disease, Autistic Spectrum Disorder (ASD) and Drug addiction.
Dose and dosage
Human
2-5 years:1 teaspoonful (5 ml) 2-3 times daily after meal for three months.6-12 years: 1-2 teaspoonful (5-10 ml) 2-3 times daily after meal for three months.Above 12 years and Adult: 2-3 teaspoonfuls (10-15 ml) 3 times daily after meal for three months.
Clinical notes
Applications:
N/A
Indication Notes:
This syrup is indicated in deficit/Cognitive deficit, Age Associated Memory Impairment (AAMI), Attention Deficit Disorder (ADD), Dementia, Convulsion and Epilepsy in children, Alzheimer’s disease, Autistic Spectrum Disorder (ASD) and Drug addiction.
Avoid In:
N/A
Contraindication Notes:
Bacopa is well tolerated but caution should be taken in hyperthyroidism, fever and acute infection. Patients with medical conditions should talk to their doctors before taking Bacopa.
The triterpenoid saponins and other bacosides are responsible for Bacopa’s ability to enhance nerve impulse transmission. The bacosides aid in repair of damaged neurons by enhancing kinase activity, neuronal synthesis, restoration of synaptic activity and modulating the cholinergic and GABAergic neurotransmission, and ultimately improves nerve impulse transmission.Bacosides appear to have antioxidant activity in the hippocampus, frontal cortexand striatum. Bacopa extracts modulate the expression of certain enzymes involved in generation and scavenging of reactive oxygen species in the brain. It exerts a protective effect against DNA damage in astrocytes and human fibroblasts.Asparagus racemosus is a well-known nervine tonic. It plays the role of an antioxidant by attenuating free radical induced oxidative neural damage. Antioxidant compound racemofuran of AR shows an enhancement in glutathione peroxidase (GPx) activity and glutathione content, and reduction in membranal lipid peroxidation and protein carbonyl.
Bacopa may potentiate the activity of thyroid stimulating drugs or decrease the effects of anti-thyroid medications. It is important to note that this effect is not typically expected at the normal therapeutic dose for humans. Bacopa may work to decrease the toxicity of several drugs like morphine, and other opiate drugs. It has also been shown to reduce the decline in cognitive function associated with phenytoin, an anti-seizure medication.
There are no side effects associated with the use of Bacopa in the above mentioned therapeutic doses. Bacopa has been used safely as an Ayurvedic medicine for hundreds of years.
Women who are pregnant or nursing are advised to consult with a physician prior to use Bacopa. Although medical literature has not reported any adverse effects related to fetal development during pregnancy or to infants who are breast-fed.