Nitroxynil

Active against adult Fasciola. Activity against immature flukes is low 

The main pharmacological action of nitroxynil is fasciolicidal. The lethal action against Fasciola hepatica has been demonstrated in vitro and in vivo in laboratory animals, and in sheep and cattle. The mechanism of action is thought to be due to uncoupling of oxidative phosphorylation

Local swelling, Itching, Pain, Cyst

Always administer S/C route.

Not recommended in lactating cow producing milk for human

Meat: 30days

Milk: not recommended in lactating cow