Povidone Iodine

Applications: Skin infection, skin lesions , Infected Traumatic lesions, Pyoderma, Surgical Incision, Cleansar
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Can be used as an antiseptic skin cleanser for major and minor surgical procedures. 10% Solution & 5% Ointment are indicated as an adjunct to systemic therapy in primary or secondary topical infections, infected surgical incisions, infected decubitus or stasis ulcers, pyodermas, secondarily infected dermatoses, and infected traumatic lesions. Prophylactically can be used to prevent microbial contamination in burns, incisions and other topical lesions; for degerming skin in hyperalimentation and catheter care. abrasions, minor cuts and wounds, may prevent the development of infections and permit wound healing. 1% Mouthwash Gargle is used for the treatment of acute mucosal infections of the mouth and pharynx. It is also used for oral hygiene prior to, during and after dental and oral surgery. 

contraindicated in known or suspected iodine hypersensitivity, with concurrent lithium therapy and in patients or users with thyroid disorder .

Povidone-Iodine is a stable chemical complex of polyvinylpyrrolidone (PVP) and elemental iodine. It shows non-selective broad spectrum germicidal action against all kind of microbes. It does not develop resistance in microorganisms. Unlike iodine solutions, it is nonsensitizing and does not cause pain when applied to wounds or mucous membranes. 

Absorption of iodine from Povidone-Iodine may interfere with thyroid function tests. Contamination with Povidone-Iodine of several types of tests for the detection of occult blood in faeces or blood in urine may produce false-positive results 

 Povidone-Iodine may produce local skin reactions although it is less irritant than iodine. The application of Povidone-Iodine to large wounds or severe burns may produce systemic adverse effects such as metabolic acidosis, hypernatraemia and impairment of renal function. 

 In case of mouth wash: Idiosyncratic mucosal irritation and hypersensitivity reactions may occur. Excessive absorption of iodine may produce systemic adverse effects such as metabolic acidosis, hypernatraemia and impairment of renal function. 

 Regular use of Povidone-Iodine should be avoided in pregnant or lactating animal as absorbed iodine can cross the placental barrier and can be secreted into milk. The use of Povidone-Iodine 1% Mouthwash Gargle in pregnant and lactating animal should not use for more than 14 days. 

Povidone Iodine Solution is flammable and caution is advised during surgical procedures involving hot wire cautery or diathermy