Generic medicine
Silymarin [Milk thistle]
Silymarin (Milk thistle) is indicated for the treatment and prevention of- Liver disease, (non-alcoholic & alcoholic) Liver cirrhosis, (non-alcoholic & alcoholic) Infectious hepatitis Drug-induced hepatitis Liver disease secondary to diabetes mellitus Toxicity of narcotics Fatty liver Jaundice
Dose and dosage
Human
1 capsule 2 to 3 times daily or as directed by a physician.
Clinical notes
Applications:
N/A
Indication Notes:
Silymarin (Milk thistle) is indicated for the treatment and prevention of- Liver disease, (non-alcoholic & alcoholic) Liver cirrhosis, (non-alcoholic & alcoholic) Infectious hepatitis Drug-induced hepatitis Liver disease secondary to diabetes mellitus Toxicity of narcotics Fatty liver Jaundice
Avoid In:
N/A
Contraindication Notes:
Contraindicated in patient with a known hypersensitivity to silymarin.
Silymarin, a flavonoid complex of Silybum marianum or Milk thistle, is the biologically active component. It provides hepatocellular protection through toxin blockade at the membrane level, enhances protein synthesis, antioxidant activity, anti-fibrotic activity and possible anti-inflammatory or immunomodulating effects.
Concomitant use of silymarin and butyrophenones or phenothiazines has resulted in the reduction of lipid peroxidation.
Well tolerated in the recommended dose. Occasionally a mild laxative effect may observe.
No experience is available about the use of Silymarin 70 mg or 140 mg during pregnancy and lactation. Therefore, if needed Silymarin 70 mg or 140 mg should be taken with caution according to the physician’s advice.