Sulfanilamide

Antibiotic

View Brand Names (3)

Dose and dosage

In General

Please follow the trade dose

Applications:
  • External bacterial infection
Indication Notes:

Act as antibacterial and dusting powder.

External use only.

Avoid In:

N/A

Contraindication Notes:

N/A

PABA (Para amino benzoic acid) is essential for bacterial growth & multiplication (synthesized by bacteria & supplied from environment). By different enzymatic process PABA is converted into Dihydrofolic acid at first & then Tetrahydrofolic acid. Tetrahydrofolic acid acts as a co-factor for single carbon metabolism & Nucleic acid synthesis. But due to structural similarity of PABA with Sulfonamides Dihydropteridin (essential for dihydrofolic acid synthesis) mistakenly combined with Sulfonamides instead of PABA. As a result Dihydrofolic acid synthesis is prevented. As a result bacterial DNA synthesis is interrupted. Sulfonamides are bacteriostatic in action

External use only