Tranexamic Acid

Antihemorrhagics

View Brand Names (2)

Dose and dosage

Cattle

5-25mg/kg body weight.
Horse

5-25mg/kg body weight.
Dog

10-15mg/kg body weight.
Cat

10-15mg/kg body weight.
Swine

10-15mg/kg body weight.

Applications: Surgical Bleeding, Accidental Bleeding, Nasal Bleeding, Rectal Bleeding, Uterine Bleeding, Bleeding during or before parturition, Hematuria, Bleeding due different disease conditions
-----

Tranexamic acid can be used in any hemorrhagic condition of animals

Tranexamic acid competitively and reversibly inhibits the activation of plasminogen via binding at several distinct sites, including four or five low-affinity sites and one high-affinity site, the latter of which is involved in its binding to fibrin. The binding of plasminogen to fibrin induces fibrinolysis - by occupying the necessary binding sites tranexamic acid prevents this dissolution of fibrin, thereby stabilizing the clot and preventing hemorrhage.

Albutrepenonacog alfa : Tranexamic acid may increase the thrombogenic activities of Albutrepenonacog alfa.
Alpha-1-proteinase inhibitor : Alpha-1-proteinase inhibitor may increase the thrombogenic activities of Tranexamic acid.
Alteplase : The therapeutic efficacy of Tranexamic acid can be decreased when used in combination with Alteplase.
Aminocaproic acid: Tranexamic acid may increase the thrombogenic activities of Aminocaproic acid.
Andexanet alfa: Tranexamic acid may increase the thrombogenic activities of Andexanet alfa

Meat: 2days.

Milk: 2 days