Fr. Dr. Vacc.

AVI ND HB1

Composition: Hitchner B1 strain of Newcastle Disease virus in live, freeze dried form

Drug Class: Vaccine

Manufacturer: Navana Pharmaceuticals Ltd.

Basic information

Generic Drug

Route of Administration

Nasal/Ocular/Oral

Strength / Concentration

Newcastle Disease virus Hitchner B1 strain /vial

Presentation and price

500 Doses

Taka

1 Doses

Taka

Dose and dosage

Poultry

Primary vaccination should be carried out with AVI ND HB1 by eye-drop, as from 4 days of age. Booster vaccination is recommended 3 to 4 weeks later by drinking water administration. For pullets, a second booster is recommended at 10 to 12 weeks of age.

Eye-drop method:

The freeze-dried vaccine is reconstituted in sterile distilled water at a ratio of 1000 doses/30 ml. Sterile needle and syringe should be used for this preparation. Hold the bird to be vaccinated with the head tilted to one side and dropping one drop of vaccine onto the eye of the bird. Be sure the vaccine spreads over the eye before releasing the bird.

Drinking water method:

Do not use a disinfectant in the drinking water for a period of48 hours prior to and 24 hours after vaccination. When a chlorine pump is used, switch it off for the same period of time. The waterers should be thoroughly cleaned before vaccination. No disinfectant shall be used. Close the water distribution system, raise and empty the nipple lines or empty the waterers. Water withholding period varies according to age of birds and climatic conditions (average 90 min). Prepare only the amount of vaccine to be used immediately. Use only plastic material and tools to prepare and administer vaccine. Prepare the required volume of water that will be consumed by the birds in 2 hours. This volume may change according to the climatic and environmental conditions.

Age Min. 3 - 4 weeks amount of water/1000 birds - 25 - 30 litres

From 10 weeks - 40 litres

As an aid in preserving the virus activity, neutralize the chlorine with 2.5 g of skimmed milk powder per litre of water or 15 mg of sodium thiosulfate per litre of water. Do not use water containing high concentrations of metal ions. Mix the vaccine with clean, cool, non-chlorinated water by opening the vials under the water and let stand for 10 minutes. Open the water system, lower the lines and check distribution throughout the house. When the tank is empty : fill it with a solution of skimmed milk powder, let it stand for 10 minutes, then open the water system to flush out the remaining vaccine solution in the pipeworks. Vaccine solution can be distributed also manually by workers using plastic watering cans


Applications:
  • NewCastle Disease
Indication Notes:

For the active immunization of healthy chickens and other poultry birds against Newcastle Disease.

Avoid In:

N/A

Contraindication Notes:

N/A

The vaccine is generally well tolerated. But, rarely catarrhal respiratory symptoms may appear 4 to 6 days following vaccination but disappear within few days.

Satisfactory protection can be achieved only in healthy chicken. Always round the number of doses same or up (e.g. 1000 doses for 1000 chicken), do not stretch the doses. All the chicken in the flock must be vaccinated at the same time. Administer the vaccine during the coolest time of the day. Dispose off all opened vaccine vials remaining after vaccination. Do not refreeze the reconstituted vaccine. Improper storage or handling of the vaccine may result in loss of potency and efficacy.



Store between +2°C and +8°C away from light and in a dry place. Keep all medicines out of reach of children.