Inj.
Espa-Vet
Drug Class: Antispasmodic
Generic Drug: Drotaverine Hydrochloride
View Alternative Brand Names (1)Manufacturer: Square Pharmaceuticals Ltd.
Basic information
Generic Drug
Route of Administration
Strength / Concentration
Presentation and price
10 ml vial
Dose and dosage
8-10 ml (160 mg–200 mg active substance) by I.M. or S.C. route. Repeat the dose 2–3 times/day if necessary.
In case of acute abdominal colic, inoculate slowly 8 ml product by I.V. route. The dose may be repeated 2-3 times/day by I.M. or S.C. route
8-10 ml (160 mg–200 mg active substance) by I.M. or S.C. route. Repeat the dose 2–3 times/day if necessary.
In case of acute abdominal colic, inoculate slowly 8 ml product by I.V. route. The dose may be repeated 2-3 times/day by I.M. or S.C. route
8-10 ml (160 mg–200 mg active substance) by I.M. or S.C. route. Repeat the dose 2–3 times/day if necessary.
In case of acute abdominal colic, inoculate slowly 8 ml product by I.V. route. The dose may be repeated 2-3 times/day by I.M. or S.C. route
1-2 ml by I.M. or S.C. route 1–2 times/day
1-2 ml by I.M. or S.C. route 1–2 times/day
1-2 ml by I.M. or S.C. route 1–2 times/day
0.5-1 ml by I.M. or S.C. route 1–2 times/day
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As antispastic in adjuvant treatment of digestive conditions (abdominal colic, gastric or duodenal ulcer, gastritis, enteritis, colitis, pancreatitis, spastic constipation, meteorism, spasms of cardia and pyloric sphincter, spasms of the biliary smooth muscles, biliary lithiasis, cholecystitis); spasms of urinary tract smooth muscles (renal urethral lithiasis, pyelitis, cystitis); genital disorders (uterine tetanic contractions, severe pains, abortion imminence) in dog, cat, horse and cattle. The spasmolytic action of the product also causes pain killing up to removal.
Severe hepatic, renal or cardiac failure.
Drotaverine inhibits phosphodiesterase hydrolysing cAMP, thereby increasing cAMP concentration, decreasing Ca uptake of the cells and changing the distribution of calcium among the cells. It may also have minor allosteric calcium channel blocking properties. It is a smooth muscle relaxant.
Levodopa (anti-perkinson effect may be decreased).
Arterial blood pressure may drop following too rapid intravenous injection.
There is no known case of teratogenicity in animal studies. However, the use of Drotaverine should be avoided during pregnancy and lactation
This drug is not to be administered to horses that are to be slaughtered for use in food. The administration is carried out only by the veterinarian or under his supervision. If administering by intravenous route, inject the product very slowly. Administer during pregnancy and lactation only afte previous assessment of the risk/benefit therapeutic ratio.
Store below 25° C & protect from light. Keep out of reach of children.