Bol.

Fasinil Vet

Generic Drug: Triclabendazole

View Alternative Brand Names (1)
Composition: Triclabendazole INN 900mg/bolus

Drug Class: Anti-parasitic

Manufacturer: Techno Drugs Ltd.

Basic information

Generic Drug

Triclabendazole

Route of Administration

PO

Strength / Concentration

900 mg/bol.

Presentation and price

900 mg Bol.

Taka

Dose and dosage

Cattle

Up to 75kg - 1 bolus

75-150 kg - 2 bolus

151-225kg - 3 bolus

226-300 kg - 4 bolus

301-400kg - 5 bolus
Goat

1/2 bolus/animal
Sheep

1/2 bolus/animal

Applications:
  • Fascioliasis
Indication Notes:

It is active against Fasciola hepatica, Fasciola gigantica

Avoid In:

N/A

Contraindication Notes:

N/A

The mechanism of action against Fasciola species is not fully understood at this time. In vitro studies and animal studies suggest that triclabendazole and its active metabolites (sulfoxide and sulfone) are absorbed by the outer body covering of the immature and mature worms, causing a reduction in the resting membrane potential, the inhibition of tubulin function as well as protein and enzyme synthesis necessary for survival. These metabolic disturbances lead to an inhibition of motility, disruption of the worm outer surface, in addition to the inhibition of spermatogenesis and egg/embryonic cells