Killed Vac.

KhuraVax Vet

Composition: contains Trivalent Foot and Mouth Disease Inactivated antigens O, A and Asia-1 strains, adjuvanted with mineral oil. Potency of the vaccine is >=3 PD50/dose.

Drug Class: Vaccine

Manufacturer: Incepta Pharmaceuticals LTD.

Basic information

Generic Drug

Route of Administration

SC

Strength / Concentration

Trivalent Foot and Mouth Disease Inactivated antigens O, A and Asia-1 strains, adjuvanted with mineral oil /vial

Presentation and price

5 Doses

400 Taka

10 Doses

700 Taka

Dose and dosage

Buffalo

Regardless of the age and weight of the animal, refer to the label on the container according to the following schedule.

Cattle, Buffaloes & Calves: 2 ml

Primary vaccination: 3 to 4 months of age and onwards

Booster: 1-1.5 month after primary vaccination

Revaccination: Every 6 months after booster and every 4 months in endemic areas like Bangladesh.

Goat

Regardless of the age and weight of the animal, refer to the label on the container according to the following schedule.

Goat & sheep: 1 ml

Primary vaccination: 3 to 4 months of age and onwards

Booster: 1-1.5 month after primary vaccination

Revaccination: Every 6 months after booster and every 4 months in endemic areas like Bangladesh.

Sheep

Regardless of the age and weight of the animal, refer to the label on the container according to the following schedule.

Goat & sheep: 1 ml

Primary vaccination: 3 to 4 months of age and onwards

Booster: 1-1.5 month after primary vaccination

Revaccination: Every 6 months after booster and every 4 months in endemic areas like Bangladesh.

Cattle

Regardless of the age and weight of the animal, refer to the label on the container according to the following schedule.

Cattle, Buffaloes & Calves: 2 ml

Primary vaccination: 3 to 4 months of age and onwards

Booster: 1-1.5 month after primary vaccination

Revaccination: Every 6 months after booster and every 4 months in endemic areas like Bangladesh.


Applications:
  • FMD
Indication Notes:
  • Vaccine is recommended for cattle, goat, sheep and buffaloes as a prophylactic measure against Foot and Mouth Disease
  • For disease control by routine vaccination in endemic area
  • For limiting the spread of the disease during outbreak
Avoid In:

N/A

Contraindication Notes:

FMD vaccine is not recommended for the animals that are clinically sick or severely debilitated or under stress.



Foot and Mouth Disease (FMD) vaccine is an inactivated, trivalent viral vaccine containing virus type O, A & Asia-1. The inactivated antigen is purified, concentrated, adjuvanted and ready for use. It is adjuvanted with mineral oil and Thiomersal. Mineral oil is added as adjuvant instead of Aluminium Hydroxide to ensure enhanced immune response and stability. World Animal Health Organization (OIE) recommended tissue culture FMD vaccine that has high immunogenicity and safety profile. It acts by stimulation of predominantly humoral immune response in the vaccinated animals. Potency of the vaccine is ≥3 PD50/dose. Protective immune response is induced 14 days after vaccination.

Generally no significant side effects are noticed after intramuscular route vaccination. However, swellings at the injection site may occur after vaccination. It usually resolves within few days but may last few weeks in some cases. A slight increase in rectal temperature of up to 1.2 °C for 4 days may appear in some cases.

There is no contraindication of the vaccine for pregnant animals



Infected and animals at the incubation period of disease, should not be vaccinated. The animals which are infected and suspected of being infected should not be vaccinated. Open vials should be used within 2 hours. Part-used vials of vaccine must be disposed.



The vaccine should be stored and transported between +2 0 C and +8 0 C. Antigenicity of the vaccine deteriorates if the temperature is allowed to rise above this range. Do not freeze the vaccine. Keep out of the reach of children.