Bol.

Metrodon Vet

Drug Class: Antiprotozoal

Manufacturer: Chemist Laboratories LTD.

Basic information

Generic Drug

Route of Administration

PO

Strength / Concentration

2 gm

Presentation and price

2 gm

5 Taka

Dose and dosage

Buffalo

1Bolus/40-50kg for 5-7days

For Intrauterine therapy : 1 bolus/25 kg body weight intrauterine route.

Goat

1Bolus/40-50kg for 5-7days

For Intrauterine therapy : 1 bolus/25 kg body weight intrauterine route.

Cattle

1Bolus/40-50kg for 5-7days

For Intrauterine therapy : 1 bolus/25 kg body weight intrauterine route.

Sheep

1Bolus/40-50kg for 5-7days

For Intrauterine therapy : 1 bolus/25 kg body weight intrauterine route.


Applications: Metritis, Pyometra, Retention of placenta, Vaginitis, Gingivitis, White diarrhea, Amoebiasis, Balantidiasis, Trichomoniasis, Giardiasis
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 Poultry: Anaerobic bacterial infections, Necrotic enteritis, ulcerative enteritis, gangrenous dermatitis etc Protozoal infection like Histomoniasis, Trichomoniasis etc and ascetic syndrome. 

Pigeon: Trichomoniasis (Canker). 

Dog & Cat: Anaerobic bacterial infections like meningitis, cholangitis, sepsis etc. giardiasis and other protozoal infection etc. 

Avoid In: Hypersensitivity

Metronidazole is an antibacterial and antiprotozoal drug used frequently in small animals, primarily for GI problems. It is a second-generation nitroimidazole in which the activity involves generation of free nitro radicals via metabolism within protozoa and bacteria. Metronidazole disrupts DNA in the organism via reaction with intracellular metabolite. Its action is specific for anaerobic bacteria and protozoa. Resistance is rare. It is active against some protozoa, including Trichomonas spp., Giardia spp., and intestinal protozoal parasites. It also has in vitro activity against anaerobic bacteria and Helicobacter spp.

The most severe adverse effect is caused by toxicity to the CNS. It is highly lipophilic and readily crosses the blood–brain barrier. High doses have caused lethargy, CNS depression, ataxia, tremors, seizures, vomiting, and weakness.

Fetal abnormalities have not been demonstrated in animals with recommended
doses but use cautiously during pregnancy.