Pow.

Neucomycin vet

Generic Drug: Lincomycin

View Alternative Brand Names (1)
Composition: Each gm powder contains Lincomycin Hydrochloride BP equivalent to Lincomycin 44 mg.

Drug Class: Antibiotic

Manufacturer: Incepta Pharmaceuticals LTD.

Basic information

Generic Drug

Lincomycin

Route of Administration

PO

Strength / Concentration

44 mg/gm

Presentation and price

100 gm sachet

210 Taka

500 gm sachet

840 Taka

1 Kg

1600 Taka

Dose and dosage

Poultry / Birds

1 gm/ 1-2 liter drinking water for 3-5 days,
Or
20-30 gm/100 kg feed for 3-5 days

Applications:
  • Air Sacculitis
  • CCRD
  • CRD
  • Necrotic Enteritis
  • Non Specific Enteritis
  • Infectious Synovitis
  • Dermatitis
Indication Notes:

Actions of lincomycin and clindamycin are similar enough that clindamycin can be substituted for lincomycin for most indications.

Avoid In:

N/A

Contraindication Notes:

N/A

Lincomycin is a lincosamide antibiotic. There are only two antibiotics in this group
used in veterinary medicine, lincomycin and clindamycin. Lincomycin is similar in
mechanism to clindamycin. The mechanism of action is also similar to macrolides,
such as erythromycin, and there may be cross-resistance among these drugs.
The site of action is the 50S ribosomal subunit. By inhibiting this ribosome, it decreases protein synthesis. In most bacteria, it is bacteriostatic. Lincomycin has a narrow spectrum of action. The spectrum includes primarily gram-positive bacteria (Streptococcus spp. and Staphylococcus spp.) and includes Erysipelothrix spp., Leptospira spp., and atypical bacteria such as Mycoplasma spp. Gram-negative bacteria of the Enterobacteriaceae and P. aeruginosa are inherently resistant.

The following drug interactions have either been reported or are theoretical in
humans or animals receiving lincomycin and may be of significance in
veterinary patients:
CYCLOSPORINE: Lincomycin may reduce levels
ERYTHROMYCIN: In vitro antagonism when used with lincomycin; concomitant use should probably be avoided
KAOLIN: Kaolin (found in several over-the-counter antidiarrheal preparations) has been shown to reduce the absorption of lincomycin by up to 90% if both are given concurrently; if both drugs are necessary, separate doses by at least 2 hours
NEUROMUSCULAR BLOCKING AGENTS (e.g., pancuronium): Lincomycin possesses intrinsic neuromuscular blocking activity and should be used cautiously with other neuromuscular blocking agents

Adverse effects are uncommon in dogs, cats, and pigs. Lincomycin has caused
vomiting and diarrhea in animals. Severe and even fatal enteritis can be caused by
PO administration to ruminants, horses, and small rodents.

Do not administer orally to rodents, horses, ruminants, or rabbits. PO administration to ruminants and horses can cause severe enteritis.

Do not store above 30 0C. Keep away from light and out of the reach of children.