Inj.

Nira Vet

Drug Class: Anti-histamine

Manufacturer: Opsonin Pharmaceuticals LTD.

Basic information

Generic Drug

Route of Administration

IM

Strength / Concentration

22.75 mg/ml

Presentation and price

10 ml vial

10 Taka

100 ml vial

90 Taka

Dose and dosage

Cattle

Adult: 5-10 ml/day/Animal - IM - 5-7 days.

Calf: 0.5- 2 ml/day/Animal- IM - 5-7 days.

Buffalo

Adult: 5-10 ml/day/Animal - IM - 5-7 days.

Calf: 0.5- 2 ml/day/Animal- IM - 5-7 days.

Goat

Calf: 0.5- 2 ml/day/Animal- IM - 5-7 days.

Sheep

Calf: 0.5- 2 ml/day/Animal- IM - 5-7 days.


Applications: Dermatitis, Insect Bites, Drug Allergies, skin lesions , Allergies, Toxicity

Pheniramine competes with histamine for the histamine H1 receptor, acting as an inverse agonist once bound. The reduction in H1 receptor activity is responsible for reduced itching as well as reduced vasodilation and capillary leakage leading to less redness and edema. This can be seen in the suppression of the histamine-induced wheal (swelling) and flare (vasodilation) response. Inverse agonism of the H1 receptor in the CNS is also responsible for the sedation produced by first-generation antihistamines like pheniramine. The binding of pheniramine to H4 receptors, and subsequent inverse agonism, may also contribute to reduced itching by antagonizing inflammation.

slight insomnia, drowsiness may develop & may feel fatigue. Injection may be irritant and transient hypotension or stimulation of the CNS.

Safety for the use of Pheniramine Maleate injection during pregnancy has not been established.