Bol.
Diadin Vet
Sulfadimidine
— Renata Pharmaceuticals Ltd.
5mg Sulfadimidine
Presentations
Bolus · 5mg Sulfadimidine
5 gm
৳12
Dose rules
No structured dose rules are linked to this brand yet.
Dose reference
Horse
225 mg/kg, PO, once, followed by 110 mg/kg, PO, q 24 h for 4 doses
Cattle
225 mg/kg, PO, once, followed by 110 mg/kg, PO, q 24 h for 4 doses
Calf: 247 mg/kg, PO, once, followed by 123.75 mg/kg, PO, q 24 h for 3 days as drench or drinking water
Poultry
Chicken (Excluding layers): 134–195 mg/kg, PO as medicated water, q 24 h for up to 6 day
Swine
247 mg/kg, PO, once, followed by 123.75 mg/kg, PO, q 24 h for 3 days as drench or drinking water
Clinical notes
- bronchitis
- Hemorrhagic Septicemia
- Actinobacillosis
- infection of urogenital system
- Metritis
- Abscess
- Gastrointestinal infection
- Enteritis
- salmonellosis
- Septicemia
Prevention of secondary bacterial infection
- Hypersensitivity
N/A
Sulfadimidine is a short-acting sulfonamide. It interferes with the synthesis of nucleic acids in sensitive organisms by blocking the conversion of p-aminobenzoic acid (PABA) to the co-enzyme dihydrofolic acid.
Nausea, vomiting, anorexia, diarrhoea, hypersensitivity reactions, SLE, serum sickness-like syndrome, liver necrosis and hepatomegaly, myocarditis, pulmonary eosinophilia and fibrosing alveolitis, vasculitis, hypoglycaemia, hypothyroidism, neurological reactions, jaundice and kernicterus in premature neonates
Sulfadimidine has been assigned to pregnancy category C by the FDA. Sulfonamides cross the placenta. Animal studies with high oral doses of some sulfonamides have revealed an increased incidence of cleft palate and other bony abnormalities.
Because sulfonamides compete with bilirubin for binding to serum albumin, free bilirubin levels rise in the presence of sulfonamides. Neonates are, therefore, at risk for hyperbilirubinemia, jaundice, and kernicterus when sulfonamides are administered to the mother near term
Meat: 7 days
Milk: 3 days