Generic medicine

Levofloxacin (Ophthalmic)

Levofloxacin eye drops is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following bacteria: Aerobic Gram-Positive bacteria- Corynebacterium species Staphylococcus oureus  Staphylococcus epidermidis  ... Read moreLevofloxacin eye drops is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following bacteria: Aerobic Gram-Positive bacteria- Corynebacterium species Staphylococcus oureus  Staphylococcus epidermidis  Streptococcus pneumoniae Streptococcus (Groups C/F) Streptococcus (Group G) Streptococcus viridons group Aerobic Gram-Negative bacteria- Acinetobocter Iwoffii Haemophilus influenzae Serrotia morcescens Levofloxacin also provides a promising treatment for other ocular infections including- Bacterial corneal ulcer, Blepharitis, Hordeolum & Perioperative condition.

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Clinical notes

Applications:
  • Corneal ulcer
Indication Notes:
Levofloxacin eye drops is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following bacteria: Aerobic Gram-Positive bacteria- Corynebacterium species Staphylococcus oureus  Staphylococcus epidermidis  ... Read moreLevofloxacin eye drops is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following bacteria: Aerobic Gram-Positive bacteria- Corynebacterium species Staphylococcus oureus  Staphylococcus epidermidis  Streptococcus pneumoniae Streptococcus (Groups C/F) Streptococcus (Group G) Streptococcus viridons group Aerobic Gram-Negative bacteria- Acinetobocter Iwoffii Haemophilus influenzae Serrotia morcescens Levofloxacin also provides a promising treatment for other ocular infections including- Bacterial corneal ulcer, Blepharitis, Hordeolum & Perioperative condition.
Avoid In:

N/A

Contraindication Notes:
It is contraindicated in patients with a history of hypersensitivity to Levofloxacin, to other quinolones or to any of the components of this medication
Levofloxacin eye drops is a sterile topical ophthalmic solution. It is a synthetic, broad spectrum, third generation fluoroquinolone bactericidal antibiotic, which active against a broad spectrum of Gram-positive & Gram-negative ocular pathogens. It functions by inhibiting bacterial topoisomerase IV and DNA gyrase enzymes required for DNA replication, transcription, repair and recombination.
Specific drug interaction studies have not been conducted with levofloxacin eye drops. But the systemic administration of some quinolones has been shown to elevate plasma concentrations of theophylline, interfere with the metabolism of caffeine and enhance the effects of the oral anticoagulant warfarin and its derivatives.
Side effects occurred only approximately 1-3% of patients that may include transient blurred vision, fever, foreign body sensation, headache, transient ocular burning, ocular pain or discomfort, pharyngitis and photophobia. In less than 1% of patients included allergic reactions, lid edema, ocular dryness and ocular itching.
Pregnancy Category C. Levofloxacin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Levofloxacin has not been measured in human milk. Caution should be exercised when Levofloxacin eye drops is administered to a nursing mother.
Prolonged use may result in the overgrowth of non-susceptible organisms, including fungi. If superinfection occurs, discontinue use and institute alternative therapy.

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