Rabies Vaccine

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Rabies vaccine is indicated for prophylactic immunization against rabies and treatment of patients following suspected rabies contact.Pre-exposure Immunization: Professional groups exposed to frequent contamination Veterinary surgeons (including students at veterinary colleges) ... Read moreRabies vaccine is indicated for prophylactic immunization against rabies and treatment of patients following suspected rabies contact.Pre-exposure Immunization: Professional groups exposed to frequent contamination Veterinary surgeons (including students at veterinary colleges) Technical personnel working with veterinary surgeons Laboratory personnel handling material contaminated with rabies vims Personnel in abattoirs and knackers yards Taxidermists Gamekeepers, forestry workers and naturalists in enzootic areas Infants particularly exposed to the risk of rabies Post-exposure Immunization: Treatment of subjects bitten by rabid animals or those suspected of being so Treatment of contact subjects.

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Rabies vaccine is contraindicated in the following cases:Pre-exposure: Severe fever, febrile infection, acute disease, progressive chronic diseases. Known hypersensitivity reactions to rabies vaccine or any of its componentsPost-exposure: No contraindication to post-exposure treatment, because rabies is lethal disease, any contraindication to exposure, treatment should be considered carefully before disqualifying an individual for anti-rabies treatment.

Rabies Vaccine for human use is a freeze-dried preparations of inactivated rabies virus produced on Vero cell. After reconstitution the vaccine is a clear, colorless sterile solution for intramuscular use.

Concurrent use with immunosuppressants may reduce the efficacy of vaccines.

Minor local reactions like pain, erythema, oedema, pruritus and induration at the injection site and lasting to 24-48 hours. Moderate fever, shivering, fainting, asthenia, dizziness, respiratory manifestations (dyspnoea, wheezing), fever, abdominal pain, vomiting and allergic skin reactions (urticaria, rash, itching).

Pregnancy. The potential risk of administration of rabies vaccine during pregnancy is unknown. Due to the severity of the disease, pregnancy is not considered to be a contraindication to post-exposure prophylaxis.Lactation: It is not known whether the vaccine is excreted in human breast milk. Due to the severity of the disease, breast-feeding is not considered a contraindication.

Intravenous injection is prohibited. The vaccine and anti-rabies immunoglobulin must not be administered with same syringe and in the same injection site. Before use, please carefully check package, label, appearance and the validity period. After reconstitution, the freeze-dried rabies vaccine should be administered as soon as possible. Any reconstituted vaccine should be used as soon as possible. It must be stored in a refrigerator at 2°C to 8°C and used within 8 hours after reconstitution or discarded.