Susp. Alafree
Oral Suspension · PO · 30mg / 5 ml · 50 ml
৳48
Susp., Tab.
Alafree
Fexofenadine Hydrochloride
— Apex Pharmaceuticals Ltd.
30mg / 5 ml · 120mg / tablet
Presentations
Tab. Alafree
Tablet · PO · 120mg / tablet · 1 tablet
৳6.5
Dose rules
No structured dose rules are linked to this brand yet.
Dose reference
Human
Seasonal Allergic Rhinitis-Adults and children 12 years and older: Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily In case of impaired renal function: 60 mg once daily Children from 6 to 11 years: Tablet: 30 mg twice daily or 60 mg once daily In case of impaired renal function: 30 mg once daily Children from 2 to 11 years Suspension: 30 mg or 5 ml twice daily In case of impaired renal function: 30 mg or 5 ml once daily Chronic Idiopathic Urticaria-Adults and children 12 years and older: Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily In case of impaired renal function: 60 mg once daily Children from 6 to 11 years: Tablet: 30 mg twice daily or 60 mg once daily In case of impaired renal function: 30 mg once daily Children from 6 months to less than 2 years: Suspension: 15 mg or 2.5 ml (1/2 tsp) twice daily In case of impaired renal function: 15 mg or 2.5 ml (1/2 tsp) once daily Children from 2 to 11 years: Suspension: 30 mg or 5 ml (1 tsp) twice daily In case of impaired renal function: 30 mg or 5 ml (1 tsp) once daily
Clinical notes
Applications:
N/A
Indication Notes:
Fexofenadine Hydrochloride is indicated for the relief of symptoms associated with seasonal allergic rhinitis in adults and children. It is also indicated for the treatment of uncomplicated skin manifestations of chronic idiopathic urticaria.
Avoid In:
N/A
Contraindication Notes:
Contraindicated in patients with known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients.
Fexofenadine Hydrochloride is an antihistamine with selective peripheral H1-receptor antagonist activity. It is rapidly absorbed after oral administration and peak plasma concentration is reached in 2-3 hours. It does not appear to cross the blood brain barrier.
Plasma concentration of Fexofenadine Hydrochloride have been increased when given with erythromycin or ketoconazole. Aluminium and magnesium hydroxide containing antacid reduces the absorption of Fexofenadine Hydrochloride.
Common side effects are headache, fatigue, drowsiness, nausea, dry mouth and gastrointestinal disturbances.
In case of an overdose, standard measures to remove any unabsorbed drug should be employed. Symptomatic and supportive treatment is recommended. There has been no reported case of an acute overdose of Fexofenadine hydrochloride.
US FDA pregnancy category of Fexofenadine Hydrochloride is C. So, Fexofenadine Hydrochloride should be avoided in pregnancy and lactation unless the potential benefits to the other outweigh the possible risks to the fetus.
Caution should be exercised in elderly patient and patient with decreased renal function.