Pow.

Amodis vet

Generic Drug: Metronidazole

View Alternative Brand Names (10)
Composition: Each gram contains Metronidazole BP 300 mg

Drug Class: Antiprotozoal

Manufacturer: Square Pharmaceuticals Ltd.

Basic information

Generic Drug

Metronidazole

Route of Administration

PO

Strength / Concentration

300 mg/gm

Presentation and price

100 gm sachet

135 Taka

Dose and dosage

Dog

1 g/15 kg body weight daily for 5-7 days.
Poultry

1 g/2-3 L drinking water daily for 5 days.
Pigeon

40 mg/kg once daily for 5 days or 100 mg/kg on alternate days for 3 treatments or 200
Cattle

4 g/25 kg body weight daily for 5-7 days
Cat

1 g/15 kg body weight daily for 5-7 days.
Goat

4 g/25 kg body weight daily for 5-7 days
Sheep

4 g/25 kg body weight daily for 5-7 days

Applications:
  • Metritis
  • Pyometra
  • Retention of placenta
  • Vaginitis
  • Gingivitis
  • White diarrhea
  • Amoebiasis
  • Balantidiasis
  • Trichomoniasis
  • Giardiasis
Indication Notes:

 Poultry: Anaerobic bacterial infections, Necrotic enteritis, ulcerative enteritis, gangrenous dermatitis etc Protozoal infection like Histomoniasis, Trichomoniasis etc and ascetic syndrome. 

Pigeon: Trichomoniasis (Canker). 

Dog & Cat: Anaerobic bacterial infections like meningitis, cholangitis, sepsis etc. giardiasis and other protozoal infection etc. 

Avoid In:
  • Hypersensitivity
Contraindication Notes:

N/A

Metronidazole is an antibacterial and antiprotozoal drug used frequently in small animals, primarily for GI problems. It is a second-generation nitroimidazole in which the activity involves generation of free nitro radicals via metabolism within protozoa and bacteria. Metronidazole disrupts DNA in the organism via reaction with intracellular metabolite. Its action is specific for anaerobic bacteria and protozoa. Resistance is rare. It is active against some protozoa, including Trichomonas spp., Giardia spp., and intestinal protozoal parasites. It also has in vitro activity against anaerobic bacteria and Helicobacter spp.

The most severe adverse effect is caused by toxicity to the CNS. It is highly lipophilic and readily crosses the blood–brain barrier. High doses have caused lethargy, CNS depression, ataxia, tremors, seizures, vomiting, and weakness.

Fetal abnormalities have not been demonstrated in animals with recommended
doses but use cautiously during pregnancy.

Store below 30° C and dry place, protected from light. Keep all medicines out of reach of children.