Fr. Dr. Vacc.

AVI ND Lasota+IB

Composition: contains LaSota strain of Newcastle Disease virus and the Massachusetts B48 strain of Infectious Bronchitis virus in live, freeze-dried form. 103.5 EID50.

Drug Class: Vaccine

Manufacturer: Navana Pharmaceuticals Ltd.

Basic information

Generic Drug

Route of Administration

Nasal/Ocular/Oral

Strength / Concentration

Newcastle Disease(Lasota) + Avian Infectious Bronchitis(Massachusetts) /vial

Presentation and price

1000 Doses

Taka

Dose and dosage

Poultry

One drop of RaniVax Plus Vet Booster vaccine should be administered by eye/nasal instillation or administered through drinking water at 21-24 days old Broilers/Layers/Breeders or other poultry birds as a booster dose. For pullets, second booster vaccination is recommended at 10-12 weeks of age.

Eye drop/nasal instillation method

  • - For 300 doses: mix the diluent well with freeze-dried live vaccine by sterile syringe and needle at a ratio of 300 doses/9 ml.

  • - For 500 and 1000 doses: use the supplied connector to connect the diluent vial to the freeze-dried live vaccine vial and mix well at a ratio of 500 doses/15 ml and 1000 doses/30 ml.

  • - Shake well the reconstituted vaccine gently and frequently.

  • - Hold the chick with one eye/nostril turned up. Instill one drop of vaccine in one eye/nostril by dropper. Hold the chick till blink of eye to absorb the entire vaccine. Keep finger on downward nostril during nasal instillation.


  • Drinking water method

  • - Do not use a disinfectant in the drinking water for a period of 48 hours prior to 24 hours after vaccination. If a chlorine pump is used, switch it off for the same period of time.

  • - The drinkers should be thoroughly cleaned before vaccination without disinfectant.

  • - Water withholding period may vary according to age of birds and weather conditions (average 1 to 2 hours).

  • - Prepare the required volume of water that will be consumed by the chicken in 2 hours. This volume may change according to the weather and environmental conditions.

    Age

    Amount of water/1000 chicken

    10-12 days

    10 liters

    13-18 days

    15 liters

    19-26 days

    25-30 liters

    Above 8 weeks

    40 liters or volume of water that will consumed by chicken in 2 hours

  • - Mix 2.5 gm of skimmed milk powder per liter of water as an aid in preserving the virus activity and neutralize the chlorine. Do not use water containing high concentration of metal ions.

  • - Mix the vaccine with clean, cool, non-chlorinated water by opening the vial under the water and let stand for 10 minutes.

  • - For nipple lines open the water system, lower the lines up to the normal height of the birds and check distribution throughout the house. When the tank is empty fill it with a solution of skimmed milk powder, let it stand for 10 minutes and then open the water system to flush out the remaining vaccine solution in the pipe. Vaccine solution can be distributed also manually using plastic watering cans.


Applications:
  • NewCastle Disease
  • Infectious Bronchitis
Indication Notes:

 For the active immunization of healthy chickens against Newcastle Disease and Infectious Bronchitis. The vaccine may be used for initial or re-vaccination of broilers, pullets and hens. 

Avoid In:

N/A

Contraindication Notes:

N/A

 Common: None. 

Rare: catarrhal respiratory symptoms appear 4 to 6 days following vaccination but disappear in a few days. 

 Newcastle Disease virus may cause a mild inflammation of the eyes in humans which last for 2 or 3 days. Care should therefore be taken when handling the virus to avoid contact with the eyes. Satisfactory protection can be achieved only in healthy birds. Always round the number of doses up (e.g. 20,000 doses for 19,750 birds), do not stretch dosage. All the birds in the flock must be vaccinated at the same time. Administer the vaccine during the coolest time of the day. Dispose of all opened vaccine containers remaining after vaccination, following the prescriptions of national or local regulations. Improper storage or handling of the vaccine may result in loss of potency. 

Protect from light, store at +2 degree C to +8 degree C and do not freeze. Keep out of the reach of
children. Diluent should be refrigerated before use.