Inh. Beviprex
Inhaler · INH · (9mcg + 4.8mcg) / puff · 1 inhaler
৳450
Inh.
Beviprex
Glycopyrronium Bromide + Formoterol Fumarate
— Square Pharmaceuticals Ltd.
(9mcg + 4.8mcg) / puff
Presentations
Dose rules
No structured dose rules are linked to this brand yet.
Dose reference
Human
Adults: Should be administered as 2 puffs twice daily, in the morning and in the evening.Use in patients with severe renal impairment should be considered if the potential benefit of the treatment outweighs the risk.
Clinical notes
Applications:
N/A
Indication Notes:
It is indicated for the maintenance treatment of patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
Avoid In:
N/A
Contraindication Notes:
All LABAs are contraindicated in patients with asthma without use of a long-term asthma control medication. This preparation is also contraindicated in patients with hypersensitivity to glycopyrronium bromide, formoterol fumarate or to any component of the product.
This preparation contains two bronchodilators: Glycopyrronium is a long-acting muscarinic antagonist (LAMA) and Formoterol is a long-acting β2-adrenergic agonist (LABA) with a rapid onset of action. Glycopyrronium has similar afnity to the subtypes of muscarinic receptors M1 to M5. In the airways, it exhibits pharmacological efects through inhibition of the M3 receptor at the smooth muscle leading to bronchodilation. Formoterol causes direct relaxation of airway smooth muscle as a consequence of the increase in cyclic AMP through activation of adenylyl cyclase.
Other adrenergic drugs may potentiate efect. Use with caution. Xanthine derivatives, steroids, diuretics or non-potassium sparing diuretics may potentiate hypokalemia or EDG changes. Use with caution. Diuretics: Use with caution. Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. May potentiate efect of formoterol fumarate on cardiovascular system. Beta-Blockers: Use with caution and only when medically necessary. Anticholinergics: May interact additively with concomitantly used anticholinergic medications. Avoid administrations of this combination with other anticholinergic-containing drugs.
The most common adverse reactions include cough and urinary tract infection. Possible side efects are sudden breathing problems, headache, tremor, nervousness, rash, swelling of the face, mouth and tongue, hives, increase blood pressure, chest pain, irregular heartbeat, muscle spasm, muscle weakness, eye pain or discomfort and urinary retention.
There are no data on the use of this preparation in pregnant women.
This combination should not be used with an additional medicine containing a LABA because of risk of overdose. Not indicated for the relief of acute bronchospasm Do not initiate in acutely deteriorating COPD or to treat acute symptoms If paradoxical bronchospasm occurs, discontinue this combination and institute alternative therapy Use with caution in patients with cardiovascular disorders Use with patients with convulsive disorders, thyrotoxicosis, diabetes mellitus and ketoacidosis. Be alert to hypokalemia and hyperglycemia Worsening of narrow angle glaucoma may occur. Use with caution with patients with narrow-angle glaucoma Worsening of urinary retention may occur. Use with caution with patients with prostatic hyperplasia or bladder-neck obstruction