Soln. Herplex
Ophthalmic Solution · OPH · 0.1% / ophthalmic solution · 10 ml
৳60.2
Soln.
Herplex
Idoxuridine
— Opso Saline Ltd.
0.1% / ophthalmic solution
Presentations
Dose rules
No structured dose rules are linked to this brand yet.
Dose reference
Human
Herpes simplex keratitis: As 0.1% solution: Instill 1 drop in the affected eye(s) every hour. Taper to every 2 hr or 4 times daily. Continue treatment for at least 7 days.
Clinical notes
Applications:
- Herpes simplex keratitis
Indication Notes:
Idoxuridine Eye drops is used for Skin infection, Eyes infection, Infection of reproduction organs, Herpes simplex infections of skin, External reproductive organs infection, External eyes area infection and other conditions. Idoxuridine Eye drops may also be used for purposes not listed in this medication guide.
Avoid In:
N/A
Contraindication Notes:
Contraindicated in hypersensitivity to any ingredient of this preparation.
Herpes simplex virus utilizes thymidine in the synthesis of deoxyribonucleic acid (DNA), a metabolite necessary for reproduction. Idoxuridine is identical in chemical structure to thymidine except that the 5-methyl group is replaced by iodine. When idoxuridine is substituted for thymidine in DNA, the cell is unable to utilize the DNA and reproduction ceases.
Corticosteroids may accelerate spread of viral infection.
Common side effects are eye irritation or pain, redness, itching, swelling of the eye, increased sensitivity to light and glare
Idoxuridine should be administered with caution in pregnancy or in women of childbearing potential. Idoxuridine has been reported to cross the placental barrier and to produce fetal malformations in rabbits when administered topically to the eyes of pregnant females in doses similar to those used clinically.
For topical use only. Do not exceed the frequency or duration of recommended dosage. The incidence of some adverse reactions increases with prolonged use. Idoxuridine is not effective in corneal inflammations following herpes simplex keratitis in which the virus is not present. Some strains of herpes simplex appear resistant to the action of Idoxuridine.