Cap. Logibac
Capsule · Oral · 400mg · 1 capsule
৳120
Cap.
Logibac
Ceftibuten Dihydrate
— ACME Laboratories Ltd.
400mg
· 1 capsule
Presentation
Dose rules
No structured dose rules are linked to this brand yet.
Dose reference
Human
Otitis Media- Adult Dosage: 400 mg orally every 24 hours for 10 days Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days Tonsillitis/Pharyngitis- Adult Dosage: 400 mg orally every 24 hours for 10 days Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days Bronchitis- Adult Dosage: 400 mg orally every 24 hours for 10 days Pediatric Dosage: >12 years: 400 mg orally every 24 hours for 10 days Cystitis- Adult Dosage: 400 mg orally every 24 hours for 7 days Pediatric Dosage: >12 years: 400 mg orally every 24 hours for 7 days Pneumonia- Adult Dosage: 200 mg orally every 12 hours for 7 to 14 days Pediatric Dosage: >12 years: 200 mg orally every 12 hours for 7 to 14 days Sinusitis- Adult Dosage: 400 mg orally every 24 hours for 10 to 14 days Pediatric Dosage: >12 years: 400 mg orally every 24 hours for 10 to 14 days Urinary tract Infection- Adult Dosage: 400 mg orally every 24 hours for 10 days Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
Clinical notes
Applications:
- Urinary tract infection
Indication Notes:
Ceftibuten is indicated for the treatment of individuals with mild-to-moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below. Acute Bacterial Exacerbations of Chronic Bronchitis: Due to Haemophilus influenzae (including β-lactamase producing strains), Moraxella catarrhalis (including (β-lactamase producing strains), or Streptococcus pneumoniae (penicillin-susceptible strains only). ... Read moreCeftibuten is indicated for the treatment of individuals with mild-to-moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below. Acute Bacterial Exacerbations of Chronic Bronchitis: Due to Haemophilus influenzae (including β-lactamase producing strains), Moraxella catarrhalis (including (β-lactamase producing strains), or Streptococcus pneumoniae (penicillin-susceptible strains only). Acute Bacterial Otitis Media: Due to Haemophilus influenzae (including β-lactamase producing strains), Moraxella catarrhalis (including β-lactamase producing strains) or Streptococcus pyogenes. Pharyngitis and Tonsillitis: Due to Streptococcus pyogenes.
Avoid In:
N/A
Contraindication Notes:
Ceftibuten is contraindicated in patients with known allergy to the cephalosporin group of antibiotics.
Ceftibuten is the dihydrate salt of Ceftibuten, is a semi-synthetic Cephalosporin antibiotic for oral administration. Ceftibuten exerts its bactericidal action by binding to essential target proteins of the bacterial cell wall. This binding leads to inhibition of cell-wall synthesis.
Theophylline & Antacid do not alter the pharmacokinetic profile of Ceftibuten. Ranitidine increases the Cmax & AUC of Ceftibuten.
Nausea, headache, diarrhea, dyspepsia, dizziness, abdominal pain, vomiting.
Pregnancy Category B. There are no controlled data on the use of Ceftibuten in pregnant women. Ceftibuten should be used in pregnancy only when the benefit clearly outweighs the risk. It is not known whether Ceftibuten (recommended dosage) is excreted in human milk. Because many drugs are excreted in human milk, caution should be excercised when Ceftibuten is administered to nursing women.
As with other broad-spectrum antibiotics, prolonged treatment may result in the possible emergence and overgrowth of resistant organisms. Careful observation of the patient is essential. The dose of Ceftibuten may require adjustment in patients with varying degrees of renal insufficiency. Ceftibuten should be prescribed with caution to individuals with a history of gastrointestinal disease, particularly colitis.
Renal Impairment- CrCl 5 to 29 ml/min: 2.25 mg/kg or 100 mg orally once a day CrCl 30 to 49 ml/min: 4.5 mg/kg or 200 mg orally once a day Hepatic Impairment: Dose adjustment is not necessary.
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