Brand
Mypart Mix
Insulin Aspart + Insulin Aspart Protamine
— Drug International Ltd.
(30% + 70%) / sc injection
Presentations
SC Injection · (30% + 70%) / sc injection
3 ml
৳550
Dose rules
No structured dose rules are linked to this brand yet.
Dose reference
Human
This insulin is typically dosed twice daily (with each dose intended to cover 2 meals or a meal and a snack). Individualize and adjust the dosage based on the individual's metabolic needs, blood glucose monitoring results and glycemic control goal. Dosage adjustments may be needed with changes in physical activity, changes in meal patterns, changes in renal or hepatic function or during acute illness. Dosage adjustment may be needed when switching from another insulin to this insulin. Or, as directed by the registered physician. Blood glucose should be monitored in all patients treated with insulin. Insulin regimens should be modified cautiously and only under medical supervision.Renal and Hepatic Impairment: Reduction the dose may require in these cases.
Administration: Before injecting this Insulin: Always check insulin labels before administration to make sure it is the right type of insulin. Inject this subcutaneously in the abdominal region, buttocks, thigh, or upper arm. Administer the dose within 15 minutes before meal initiation. For patients with type 2 diabetes, the dose may also be given after meal initiation. Rotate injection sites within the same region from one injection to the next to reduce the risk of lipodystrophy. According to the instruction given with MyPen, insert the cartridge into the pen correctly & equip the needle. Roll the cartridge between your palms 10 times- it is important that the cartridge is kept horizontal (level with the ground). Move the cartridge up and down 10 times so that the glass ball moves from one end of the cartridge to the other. Repeat the rolling and moving procedures until the liquid appears uniformly white and cloudy. Do not use the cartridge if the resuspended insulin does not look uniformly white and cloudy. This must be resuspended immediately before use. Resuspension is easier when the insulin has reached room temperatue. Remove the needle cap, discharge air bubbles in the cartridge. Adjust the dosage button to get correct dose & inject to the specific site. Always use a new needle for each injection to prevent contamination. Do not administer this insulin intravenously or use in insulin infusion pumps. Do not use this insulin past the expiration date printed on the label. Do not mix this insulin with any other insulins. Complete the other stages of injection without delay. Check that there are at least 12 units of insulin left in the cartridge to allow even resuspension. If there are less than 12 units left, use a new cartridge.
Clinical notes
Applications:
N/A
Indication Notes:
This is a mixture of Insulin Aspart and Insulin Aspart Protamine indicated to improve glycemic control in patients with diabetes mellitus.
Avoid In:
N/A
Contraindication Notes:
Insulin Aspart is contraindicated during episodes of hypoglycemia, in patients with hypersensitivity to this drug or one of its excipients.
Insulin Aspart & Insulin Aspart Protamine is a human insulin analog suspension containing 30% Insulin Aspart & 70% Insulin Aspart Protamine used to lower blood glucose. Insulin Aspart is homologous with regular human insulin with the exception of a single substitution of the Amino Acid Proline by Aspartic Acid in position B28, and is produced by recombinant DNA technology utilizing Saccharomyces cerevisiae (baker's yeast). The primary activity of insulin, including Insulin Aspart is the regulation of glucose metabolism. Insulin, and its analogs lower blood glucose by stimulating peripheral glucose uptake, especially by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulin inhibits lipolysis and proteolysis, and enhances protein synthesis.
A number of drugs affect glucose metabolism and may require dose adjustment. The following substances may reduce the insulin requirements: anti-diabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analog and sulfonamide antibiotics. The following substances may increase the insulin requirements: atypical antipsychotics, corticosteroids, danazol, diuretics, estrogen, glucagon, isoniazid, niacin, oral contraceptives, phenothiazine, progestogens, preotease inhibitors, somatropin, sympathomimetic agents and thyroid hormones. Beta-blockers, clonidine, lithium salts, alcohol and pentamidine may either potentiate or weaken the blood glucose lowering effect of insulin. Beta-blockers, clonidine, guanethidine and reserpine may blunt the signs and symptoms of hypoglycemia.
Most common side effects are hypoglycemia, hypersensitivity and allergic reactions, hypokalemia, injection site reaction, lipodystrophy, pruritus and rash.
Excess insulin administration may cause hypoglycemia and, particularly when given intravenously, hypokalemia. Mild episodes of hypoglycemia usually can be treated with oral glucose. Adjustments in drug dosage, meal patterns, or exercise may be needed. Hypokalemia must be corrected appropriately.
Pregnancy category B. There are no available data in pregnant women to inform a drug-associated risk. There are risks to the mother and fetus associated with poorly controlled diabetes in pregnancy. There are no data on the presence of Insulin in human milk, the effect on breastfed infants, or the effect on milk production.