UroSafe

• Urinary tract infection

Cranberry is indicated for- The treatment and prevention of urinary tract infection. Kidney stones.

N/A

Potential contraindications of cranberry may be present with renal insufficiency and in persons with the potential for developing uric acid or calcium oxalate stones.

Cranberry (Vaccinium macrocarpon) is a native North American plant commonly used for reduction in urinary tract infections (UTIs) occurrence and kidney stone management. Cranberry reduces the need for repeated antibiotic use in the treatment of recurrent urinary tract infection. Bacterial adherence to mucosal surfaces is generally considered to be the initial event in the pathogenesis of most infectious diseases due to bacteria in human such as UTIs. Cranberry inhibits adherence of bacteria to the lining of the urinary bladder and urethra. At higher dose it also works as a urinary antiseptic and reduces incidence of stone formation. Recent publications show as much as 65% reduction in UTI with cranberry consumption leading to reduced use of antibiotics and reduction in the number of incidences of recurrent cystitis.

No known interactions with antibiotics or other drugs. Cranberry enhances vitamin B12 absorption, which is useful for patients taking omeprazole, a drug used to treat ulcers.

Well tolerated in recommended dose. Occasionally diarrhea or mild gastrointestinal upset may occur at high dose.

No known restrictions during pregnancy or lactation.