Bol. Fasinil Vet
Bolus · Oral · 900mg Triclabendazole · 900 mg
Bol.
Fasinil Vet
Triclabendazole
— Techno Drugs Ltd.
900mg Triclabendazole
· 900 mg
Presentation
Dose rules
No structured dose rules are linked to this brand yet.
Dose reference
Cattle
5-10mg/kg body weight
Sheep
10mg/kg body weight
Goat
10mg/kg body weight
Clinical notes
Applications:
N/A
Indication Notes:
It is active against Fasciola hepatica, Fasciola gigantica
Avoid In:
N/A
Contraindication Notes:
N/A
The mechanism of action against Fasciola species is not fully understood at this time. In vitro studies and animal studies suggest that triclabendazole and its active metabolites (sulfoxide and sulfone) are absorbed by the outer body covering of the immature and mature worms, causing a reduction in the resting membrane potential, the inhibition of tubulin function as well as protein and enzyme synthesis necessary for survival. These metabolic disturbances lead to an inhibition of motility, disruption of the worm outer surface, in addition to the inhibition of spermatogenesis and egg/embryonic cells