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Titex Vet

Drug Class: Antibiotic

Manufacturer: Incepta Pharmaceuticals LTD.

Basic information

Generic Drug

Route of Administration

PO

Strength / Concentration

200 mg

Presentation and price

100 gm

Taka

1 Kg

Taka

Dose and dosage

Cattle

1gm/10-20 kg body weight once daily for 3-7 days.

Buffalo

1gm/10-20 kg body weight once daily for 3-7 days.

Goat

1gm/10-20 kg body weight once daily for 3-7 days.

Sheep

1gm/10-20 kg body weight once daily for 3-7 days.


Applications: Anthrax, Babesiosis , Black Quarter (Duplicate), Diarrhea, Dysentery , Hemorrhagic Septicemia, Mastitis, Pneumonia, Brucellosis, Calf Scour, Infectious enteritis, Navel ill, Pyometra, Metritis, Peritonitis, Kiptospirosis, Infectious pleuropneumonia, Calf Diphtheria, Castration, Paratyphoid, foot-rot, salmonellosis, Actinomycosis, anaplasmosis, Colibacillosis, Necrotic Enteritis, Fowl Cholera, Infectious coryza, Streptococcosis, Staphylococcosis
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Prevention of secondary bacterial infection caused by FMD, Ephemeral fever, PPR etc.
Avoid In: Hypersensitivity

Oxytetracycline is one of the oldest tetracycline antibiotics used in animals.
The mechanism of action of tetracyclines is to bind to 30S ribosomal subunit and inhibit protein synthesis. Oxytetracycline is usually bacteriostatic. It has a broad spectrum of activity, including gram-positive and gram-negative bacteria, some protozoa, Rickettsia spp., and Ehrlichia spp. The spectrum also includes Chlamydia spp., spirochetes, Mycoplasma spp., L-form bacteria, and some protozoa (Plasmodium spp. and Entamoeba spp.). Resistance is common among gram-negative bacteria of the Enterobacteriaceae (e.g., Escherichia coli) and Staphylococcus spp.

Tetracyclines have produced kidney injury, but this has been rare with recommended doses. Tetracyclines can affect bone and teeth formation in young animals, but this is usually not a problem with short-term administration. Tetracyclines have caused drug fever in cats, but the mechanism is unknown. Oxytetracycline administration to horses has been associated with colic and diarrhea because of changes in the intestinal bacterial flora.
Azotemia can be seen with high doses, which is attributed to inhibition of protein synthesis in mammalian cells. At very high doses, oxytetracycline can injure other organs (e.g., liver) or cause metabolic acidosis, hemoglobinemia, or myoglobinemia, and the kidneys are injured as a consequence.
Avoid injection volumes for IM greater than 10 mL per site in cattle and greater than 5 mL in pigs because of injection-site lesions

Meat: 7-8 days

Milk: 2 days.

For long acting: Meat 14 days milk 7days.

Do not store above 30 degree centigrade, avoid freezing. Store the vial in the carton to protect from light. Keep out from the reach of children.