Inj.

Vermishin Plus

Drug Class: Anti-parasitic

Manufacturer: Shinil Pharma Ltd.

Basic information

Generic Drug

Route of Administration

SC

Strength / Concentration

10+100 mg/ml

Presentation and price

5 ml vial

75 Taka

Dose and dosage

Horse

1ml / 50kg body weight. Repeat after 14 days.

Goat

1ml / 50kg body weight. Repeat after 14 days.

Sheep

1ml / 50kg body weight. Repeat after 14 days.

Dog

1ml / 10kg body weight. Repeat after 14 days.

Cattle

1ml / 50kg body weight. Repeat after 14 days.

Buffalo

1ml / 50kg body weight. Repeat after 14 days.

Cat

0.25ml / 5kg body weight. Repeat after 14 days.


Applications: Nematodes, Lung Worm, Flies, Lice, Tick, Mites, Humpsore
-----

Gastrointestinal Roundworms (adults and fourth-stage larvae):
Ostertagia ostertagi (including inhibited O. ostertagi)
O. lyrata
Haemonchus placei
Trichostrongylus axei
T. colubriformis
Cooperia oncophora
C. punctata
C. pectinata
Bunostomum phlebotomum
Nematodirus helvetianus (adults only)
N. spathiger (adults only)
Oesophagostomum radiatum
Lungworms (adults and fourth-stage larvae):
Dictyocaulus viviparus
Liver Flukes:
Fasciola hepatica (adults only)
Cattle Grubs (parasitic stages):
Hypoderma bovis
H. lineatum
Sucking Lice:
Linognathus vituli
Haematopinus eurysternus
Solenopotes capillatus
Mange Mites (cattle scab1):
Psoroptes ovis (syn. P. communis var. bovis)
Sarcoptes scabiei var. bovis

Horses: not be used in foals less than 4 months old

Dog: not recommended for use in puppies less than 6 weeks old.

Ivermectin enhances the release of gamma amino butyric acid (GABA) at presynaptic neurons. GABA acts as an inhibitory neurotransmitter and blocks the post-synaptic stimulation of the adjacent neuron in nematodes or the muscle fiber in arthropods. By stimulating the release of GABA, ivermectin causes paralysis of the parasite and eventual death. 

Toxicity may occur at high doses and in breeds in which ivermectin crosses the
blood–brain barrier.

Sensitive breeds include collies, Australian shepherds, Old
English sheepdogs, longhaired whippets, and Shetland sheepdogs. 

Toxicity is neurotoxic and signs include hypersalivation, depression, ataxia, difficulty with
vision, coma, and death.

Toxicity may occur at high doses and in breeds in which ivermectin crosses the
blood–brain barrier.

Toxicity is neurotoxic and signs include hypersalivation, depression, ataxia, difficulty with
vision, coma, and death.